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Trial Search

Current Search Criteria:

Intervention: Euglycemic clamp with Humalog®

Found 13 matching trials

A Double-blinded, Randomised, Two -Period Crossover Euglycemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Insulin Lispro and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

PHASE1

The addition of Biochaperone to insulin lispro may accelerate the onset and...

Status

Completed

Location

Multiple Locations

Start Date

2013-12

Trial ID

NCT02029924

Treatments Being Tested

BioChaperone insulin lispro Humalog®

A Trial Comparing the Pharmacodynamics and Pharmacokinetics of BC Combo THDB0207 and Lantus® and Humalog® in Subjects With Type 1 Diabetes

PHASE1

This is a randomised, double-blind, three-period crossover euglycaemic clam...

Status

Completed

Location

Profil Institut für Stoffwechselforschung GmbH

Start Date

2022-05-12

Trial ID

NCT05373199

Treatments Being Tested

Euglycemic clamp with BC Combo THDB0207 Euglycemic clamp with Lantus®Euglycemic clamp with Humalog®

A Trial Investigating the Pharmacodynamics of BC Combo THDB0207 Compared With Humalog® Mix25 and Simultaneous Injections of Humalog® and Lantus® in Healthy Chinese Volunteers

PHASE1

This is a randomised, double-blind, double-dummy, active-controlled, three-...

Status

Completed

Location

Profil Institut für Stoffwechselforschung GmbH

Start Date

2022-05-12

Trial ID

NCT05373186

Treatments Being Tested

Euglycemic clamp with BC Combo THDB0207 Euglycemic clamp with Humalog® Mix25 Euglycemic clamp with Humalog® and Lantus®

A Trial to Evaluate the Pharmacokinetic and Pharmacodynamic Properties of BioChaperone® Insulin Lispro, Fiasp® and NovoRapid® Delivered by an Insulin Pump

PHASE1

This is a single-centre, randomised, double-blind, three-period, complete c...

Status

Completed

Location

Profil Institut für Stoffwechselforschung GmbH

Start Date

2017-06-20

Trial ID

NCT03179332

Treatments Being Tested

BioChaperone® insulin lispro Fiasp®Novorapid®

Single Ascending Dose Study of MK-1092 in Healthy Participants and in Participants With Type 1 and Type 2 Diabetes Mellitus (MK-1092-001)

PHASE1

This is an active- and placebo-controlled, single-site, four-part trial of ...

Status

Completed

Location

ProSciento Inc. ( Site 0001)

Start Date

2017-08-16

Trial ID

NCT03170544

Treatments Being Tested

MK-1092, 4.0 nmol/kg MK-1092, 8.0 nmol/kg MK-1092, 16 nmol/kg MK-1092, 32 nmol/kg MK-1092, 64 nmol/kg Glargine 3.0 nmol/kg Lispro 1.2 nmol/kg Placebo to glargine Placebo to MK-1092 Dextrose Insulin

A Double-blinded, Randomised, Three-period Crossover Euglycaemic Clamp Trial Investigating the Pharmacokinetics, Glucodynamics and Safety of BioChaperone Human Insulin, Human Insulin (Huminsulin® Normal) and Insulin Lispro (Humalog®) in Subjects With Type 1 Diabetes

PHASE1

The addition of BioChaperone to already marketed prandial human insulin pre...

Status

Completed

Location

Profil GmbH

Start Date

2014-08

Trial ID

NCT02213146

Treatments Being Tested

BioChaperone human insulin Huminsulin® Normal Humalog®

A Trial to Compare BioChaperone Insulin Lispro Formulations With US Approved Humalog® and With EU Approved Humalog® in Patients With Type 1 Diabetes Mellitus

PHASE1

This is a single-centre, randomised, double-blind, 4-way crossover, 4-treat...

Status

Completed

Location

Profil GmbH

Start Date

2020-08-03

Trial ID

NCT04501107

Treatments Being Tested

Administration of BioChaperone insulin lispro reconstituted with Humalog® (IMP1)Administration of Ready-to-use BioChaperone insulin lispro (IMP2)Administration of US-approved Humalog® (IMP3)Administration of EU-approved Humalog® (IMP4)

PK/PD Biosimilarity Study of Gan & Lee Insulin Lispro Injection vs. EU and US Humalog® in Healthy Males

PHASE1

Primary objective: To demonstrate pharmacokinetic (PK) and pharmacodynamic...

Status

Completed

Location

Profil Mainz GmbH & Co. KG

Start Date

2019-04-23

Trial ID

NCT04235439

Treatments Being Tested

Gan & Lee Insulin Lispro Injection

A Trial to Investigate the Dose-linearity of BioChaperone® Combo 75/25 and the Safety at Three Different Doses in Subjects With Type 2 Diabetes

PHASE1

This is a bicentric, double-blinded, randomised, four-period crossover phas...

Status

Completed

Location

Profil Mainz GmbH & Co. KG

Start Date

2017-06-06

Trial ID

NCT03180710

Treatments Being Tested

BioChaperone® Combo 75/25 at 0.6 U/kg BioChaperone® Combo 75/25 at 0.8 U/kg BioChaperone® Combo 75/25 at 1.0 U/kg Humalog® Mix25 at 0.8 U/kg

A Study to Compare Pharmacokinetics and Pharmacodynamics of SAR342434 to Insulin Lispro in Subjects With Type 1 Diabetes

PHASE1

Primary Objective: To compare exposure and activity of SAR342434 to US-app...

Status

Completed

Location

Sanofi Administrative Office

Start Date

2013-03

Trial ID

NCT02273258

Treatments Being Tested

SAR342434 Insulin Lispro Insulin Lispro

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